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Below is a scientific explanation of the mechanisms explored in published studies: 1

Heavy smokers and drinkers can also have low levels of B12

Plant Physiol 141(2):391396 Begara-Morales JC, Chaki M, Valderrama R, Mata-Prez C, Padilla M, Barroso JB (2019) Transcriptional regulation of gene expression related to hydrogen peroxide (H2O2) and nitric oxide (NO)