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They reported an improved rate of collagen formation

According to NICE Clinical Knowledge Summaries and the British National Formulary , the standard treatment is intramuscular injections of 1,000 mcg (1 mg) hydroxocobalamin

Vitamin B12 supplementation supports energy levels that can dip during caloric restriction, and some compounding pharmacies offer tirzepatide pre-mixed with B12

In one clinical trial assessing the efficacy of phentermine and vitamin B-12 for weight loss, vitamin B-12 injections were used as the sole ingredient of 1,000 mg per week