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The MDA content was calculated as follow: [6.45 (OD 532 OD 600 ) 0.56 OD 450 ] Vt /( Vs m ), where Vt represents the total volume of the extraction solution, Vs the volume of the extraction solution taken during the determination, and m represents the mass of the sample (23)

In our exploratory analyses, we observed a significant condition-by-sex interaction for Glx/tNAA change, with male participants showing more pronounced differences between placebo and naltrexone pretreatment conditions compared to females

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We first compared the differences between these two compounds in improving the phenotype of mice with NASH

Tolerant genotype VA13 showed lower electrolyte leakage compared to sensitive genotype