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However, whether the purified R-isomer actually presents significant clinical advantages is unproven (Galanter & Boushey, 2015)

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Nat Rev Cardiol 18(11):785802 (2021) Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants

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