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Limitations They require cleaning to prevent buildup and smell

Concurrent use of both cannabis and tobacco was associated with increased risk (even adjusted for age, asthma, and comorbidities) of respiratory symptoms (OR 2.39, 95% CI 1.583.62) and COPD (OR 2.90, 95% CI 1.535.51) if the lifetime dose of marijuana exceeded 50 marijuana cigarettes

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Again, emissions of formaldehyde, acetaldehyde, and acrolein--all either carcinogens or respiratory irritants--increased with usage