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The requirements for license and registration for manufacturers will similarly hurt small companies while helping to give companies with better funding and facilities a competitive edge

Curr Med Chem 20(12):14961530 Kaluza J, Larsson SC, Orsini N, Linden A, Wolk A (2017) Fruit and vegetable consumption and risk of COPD: a prospective cohort study of men

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However, Vuse lost its top position in 2017, when Juul overtook it to become the most popular e-cigarette in the US