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rxlist.com (Xanax ) Keywords Clonazepam Trade Name: Klonopin Drug Class: Benzodiazepine, antiseizure Indications: Lennox-Gastaut syndrome (petit mal variant) seizure disorder Akinetic and myoclonic seizures Absence seizures (petit mal) who have failed to respond to succinimides Off Label: other anxiety & seizure disorders, adjunctive for treatment of acute psychosis, insomnia Contraindications: If clonazepam is being used to treat a seizure disorder, flumazenil should not be used to reverse the effects of benzodiazepines, because it may precipitate seizures Pharmacokinetics: Long half life of 30-40 hours CYP3A4 metabolism References: Stahl SM (2009): The Prescriber's Guide