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As a result, it may be useful in lowering the toxicity produced by other tobacco components [69]

Nicotine promotes neutrophil polarization/activation to N2 phenotype in a STAT3-dependent manner To gain further insight into the functional properties of nicotine-treated neutrophils, we assessed in vitro polarization of human and mouse primary neutrophils using N1-/N2-associated markers 66,67

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