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Ozzy Osbourne, the prince of darkness and godfather of heavy metal, has died aged 76, just weeks after he reunited with Black Sabbath band-mates for a farewell concert in his hometown of Birmingham in England

One day prior to presentation, the patient developed left-sided chest pain described as sharp and pleuritic in nature, which lasted several seconds and occurred intermittently without identifiable triggers or alleviating factors

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In a human study including nonsmokers, EC users, and cigarette smokers, circulating ASC, caspase-1, and IL-1 showed exposure-related changes that were consistent with altered inflammasome signaling

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