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1 Japan Japan has the highest prevalence of heated tobacco product use and is the country where heated tobacco products have captured the highest share of the tobacco market, allowing us to evaluate the real-world effects of HTPs on the combustible tobacco market
Many of these effects were attributed to the presence of nicotine compared to nicotine-free electronic cigarettes (22, 24, 27, 30, 45, 46, 48) (Figure 2)
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