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As nicotine is a psychoactive substance, adolescent tobacco use represents an important form of substance misuse, often co-occurring with other risk behaviours (19)

What to expect during the procedure Procedures using endoscopy usually take one to two hours

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Non-medical interventions In medically refractory cases, percutaneous coronary intervention could be attempted if an obstructive lesion is thought to be the persistent trigger of localized vasospasm

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