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A number of studies have provided evidence that cigarette smoking is a major cause of gastrointestinal (GI) disorders, which include chronic inflammation, such as peptic ulcers and inflammatory bowel disease (IBD), and cancers of the GI tract (1,38)

Filtered cigars often have a looser draw due to the presence of a filter

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PMID: 30887394

Again, folic acid deficiency may lower the assayable levels of B12 while increasing homocysteine levels