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This alkaloid is further metabolized to various alkaloids such as Nformylnornicotine, nornicotine, myosmine, nicotyrine, and cotinine [35]

Notably, only 1 participant in the ACNP group voluntarily withdrew due to job changes, while the remaining 9 participants discontinued treatment because of the impact of the COVID-19 epidemic (Figure 2)

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Excessive salivation and angular cheilitis

2 - "Risks associated with smoking cigarettes with low machine-measured yields of tar and nicotine", Smoking and tobacco control, Monograph 13, National Institutes of health, National Cancer Institute (accessible en ligne)