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However, it has been found that the nicotine yield of individual products has only a small effect (4.4%) on the blood concentration of nicotine, [159] suggesting "the assumed health advantage of switching to lower-tar and lower-nicotine cigarettes may be largely offset by the tendency of smokers to compensate by increasing inhalation"

Transitions between cigarette, ENDS and dual use in adults in the PATH study (waves 14): multistate transition modelling accounting for complex survey design

After that, you might still feel some lingering effects, but they wont be as strong

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