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Besides altered myelination, patients with BD show altered neurotrophic factors, especially BDNF which was reported to be deficient in both serum [137] and brains of BD patients [138]

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4 GSH and thioredoxin (Trx) directly neutralize electrophiles and recycle oxidized proteins

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Allergic Reactions: Although rare, allergic reactions to BPC-157 have been reported in a few instances in the medical literature

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ROCK activation is modulated by RhoA GTPase, which in turn is activated through upstream signaling by a diverse group of proteins including angiotensin II, endothelin-1, fibroblast growth factor (FGF), and transforming growth factor-beta (TGF-), amongst others (Seccia et al., 2020)

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