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Collectively, these elements provide a global assessment of cigarette butt contamination that directly informs environmental protection, tobacco regulation, and waste management policies, supporting the development of global policies, such as the United Nations Plastic Treaty, and the implementation of existing agreements, such as the World Health Organization Framework Convention on Tobacco Control [38]

Consecutive patients with a newly diagnosed head and neck cancer were prospectively enrolled between 2011 and 2015 in a tertiary center in Hamilton, Ontario [67]

Other reports, such as by Kadir & Sarani (2015), indicate that some toxic effects can occur from one cigarette butt even at concentrations of one cigarette butt per 4,000 liters