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It also examines trends in tobacco and vaping use, the effectiveness of e-cigarettes to treat tobacco addiction, and the differences in health effects of vaping in people who smoke, vape or do neither, the role of the tobacco industry in the rising use of e-cigarettes, and the ethical dilemmas presented by e-cigarettes

Despite its clinical importance, the epidemiology and risk factors for APE remain underreported, especially in neurologically compromised populations

Iwai T and Umeda M