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In the vast majority of counties, males smoked cigarettes at higher rates than females (Figure 4): in 99.0% of counties in 1996 males had a higher cigarette smoking prevalence than females, while in 2012 the same was true in 96.4% of counties

It may also be mixed with street drugs and synthetic opioids to mask low purity

Past research has already shown that vaping, similar to smoking, is linked to changes in gene expression involved in the development of cancer, as well as certain heart and lung diseases

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