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Continuous nicotine exposure produces cumulative desensitization , with your receptors gradually losing responsiveness even while the drug remains present

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Avoid rubbing to preserve molecular integrity

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Each required warning statement must appear directly on the package and must be clearly visible underneath any cellophane or other clear wrapping as follows, per 21 CFR 1143.5(a): Be located in a conspicuous and prominent place on the two "principal display panels" of the package and the warning area must comprise at least 30 percent of each of the principal display panels