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In a murine COPD model, prolonged CS exposure (12 weeks) markedly increased the expression of glucose transporter 3 (GLUT-3) in lung tissue, whereas GLUT-3 knockout significantly alleviated airway remodeling and lung function impairment, and inhibited epithelialmesenchymal transition (EMT) in bronchial epithelial cells

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The occurrence of these lesions is prevalent among individuals who engage in cigarette consumption, and their potential transformation into malignant tumors can be mitigated through the implementation of thorough screening protocols, timely diagnosis, and suitable therapeutic interventions [10, 11]

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