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However, the calorie-burning effects of tobacco are not significant and are outweighed by the negative health consequences of smoking

Second, we estimated multivariable linear regression models of cigarettes smoked per day, conditional on the frequency of vaping (categorized as every-day, some-days, ever but no longer, never), psychological distress (categorized as NPD, MPD, and SPD), the interaction of vaping and psychological distress (these variables were demeaned, or centered so that main effect coefficients could be directly interpreted 26 ), and other covariates described above

As indicated by the PC 20 value, the two groups did not differ in airway hyperresponsiveness (Table 1)

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