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GST enzymes, especially GSTM1 and GSTT1, are responsible for conjugating SFN with glutathione, a step traditionally viewed as a detoxification and excretion pathway

The use of different methodologies yielded complementary findings but also allowed a critical view on performance and inherent limitations of each method

Take-home message: - Binders are natural substances, like clay and charcoal, that the wellness industry is selling, claiming that they bind to toxins during a cleanse to prevent you from feeling ill and to stop the body from reabsorbing the toxins - The idea that we need to regularly detox our bodies is not based on good science

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