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these can generate reactive species upon combustion, irritate or sensitize mucosal surfaces, induce inflammation, and may have cytotoxic or carcinogenic properties

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Most other studies have not been prospective, but have, instead, asked people to look back and recall when they started smoking

The authors estimated 30.5 to 42.1 percent of packs were trafficked.[3] Smuggling takes many forms: counterfeit state tax stamps, counterfeit versions of legitimate brands, hijacked trucks, or officials turning a blind eye.[4] The studys authors, LaFaive and Nesbit, cite examples of a Maryland police officer running illicit cigarettes while on duty, a Virginia man hiring a contract killer over a cigarette smuggling dispute, and prison guards caught smuggling cigarettes into prisons