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13 Even the tobacco industrys own studies have concluded that in vitro toxicology tests can be successfully used both for better understanding the biological activity of cigarette smoke and for guiding the development of cigarettes with reduced toxicity. 14 Despite this fact, tobacco companies, government agencies, 15 the American Cancer Society, National Heart, Lung and Blood Institute, among other organization and, yes, even anti-smoking groups continue to test cigarettes on animals
In addition, first-generation and advanced users did not differ in baseline exhaled CO, e-cigarette dependence, or concentration of nicotine used in the e-liquid
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