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A 2018 in vitro study found that exposure to e-juice flavoring compounds may trigger an inflammatory response in white blood cells

However, the nature of the risk differs significantly

In 2017, more than two million middle- and high-school students used e-cigarettes, according to the Centers for Disease Control and Prevention

A 2007 report on activities of the European Commission indicates that between 50 percent and 75 percent of seizures involved counterfeit cigarettes