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For reference, we also examined the effects of mainstream cigarette smoke (MCS), and to examine its contribution to e-cig toxicity, we studied the effects of acrolein, the aldehyde most implicated in the cardiovascular toxicity of smoking 21,31

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Its really impossible to predict, said the director of the FDAs tobacco center, Mitch Zeller, who noted that a previous regulation on menthol received more than 175,000 comments, all of which the FDA was required to consider