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The burden should always be on manufacturers to show that their products would not appeal to youth before going to market

The sites can be formed when certain relatively unstable DNA adducts, such as 7-methyldeoxyguanosine, lose their purine base (in this case 7-methylguanine) due to spontaneous decomposition or hydrolysis

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Warning tones, headlamp on, key-in-ignition, driver safety belt unfasten, turn signal on