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SELECT-SWITCH Study Design Intro: 12-week, randomized, double blind, head-to-head (H2H), Phase 3b/4 study that evaluated the efficacy and safety of RINVOQ (upadacitinib) + MTX versus HUMIRA (adalimumab) + MTX in 491 adult patients with moderate to severe RA who demonstrated prior failure to one non-adalimumab TNF inhibitor

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Undergraduate students, who had currently been smoking, had quit and never smoked, were selected through purposive sampling and invited to participate in the study