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National Cancer Institute (Report)

NtZIP1-like is involved in supplying internal tissues of younger organs with Zn (primarily under deficiency), while NtZIP11 specifically participates in the uptake of Zn excess in plants exposed to its high, toxic concentrations, contributing to the accumulation of a high amount of this metal in older tobacco leaves (Papierniak et al

Many previous studies included women, who rarely smoke cigars, and young men, among whom death is rare

higher risks are associated with frequency of use