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doi:10.1146/annurev-physiol-042924-084007

The size, number and distribution of aerosolized particles and how they affect human biological systems is highly dependent on a number of factors including, but not limited to, the temperature generated by the voltage of the ECIG battery, the construction of the ECIG device, the composition of the E-liquid itself and the puffing topography used by individuals inhaling the aerosol

Scientists specifically choose to study samples from e-cigarette consumers rather than purchasing e-cigarettes from a store or company in order to assess typically used devices

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