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Smoking can aggravate or initiate: Chilblains Frostbite Primary or secondary vasospastic disease (Raynaud phenomenon) Ulceration, in patients with systemic sclerosis Thromboangiitis obliterans (Buerger disease), in which blood clots occur in small blood vessels Cholesterol emboli associated with atherosclerosis Thrombosis caused by thrombophilia, antiphospholipid syndrome or drugs including oral contraceptives

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However, we are happy to hear from you via e-mail and telephone using the good old-fashioned ways of contact

It began its life as a co-commission between the Philadelphia Orchestra, the Indianapolis Symphony Orchestra and the Dallas Symphony Orchestra