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Cigarette smoke has been shown to induce atherogenesis through a multitude of mechanisms that include endothelial dysfunction, chronic inflammation, promotion of thrombosis, and alteration of lipid metabolism 1,5

Larger amounts of nicotine are inhaled with blunts or full-size cannabis cigars

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Thats a loss of more than 200 SAPIS workers since 2006, due to the expiration of a federal grant, according to the union

So, while we believe the modifications are an improvement in the modeling, they do not cause major shifts in the estimated smuggling outcomes