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122 Prior to 2009, restrictions on the distribution of tobacco products were largely enforced at the state level, and promotion of cigarettes and smokeless tobacco was largely overseen by the Federal Trade Commission (FTC)

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see the Hazardous Substances Data Bank for more information.[6] In 2020, acrolein was classified by the International Agency for Research on Cancer as probably carcinogenic to humans (Group 2A).[7] This decision was based on sufficient evidence of the carcinogenicity of acrolein in two rodent species (mice and rats), and strong evidence that acrolein shows many key characteristics of carcinogens.[7,8] Other health effects associated with acrolein exposure include eye and respiratory irritation, and changes in lung function and tissue damage within the respiratory tract.[2,9] Acute exposure may lead to respiratory distress, eye and nasal irritation, and skin irritation or burns.[10] Regulations and Guidelines Occupational exposure limits (OEL)[11,12,13,14,15,16,17,18,19,20,21,22,23,24,25] ppm = parts per million sk = easily absorbed through the skin stel = short term exposure limit (15 min

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