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Conversely, inhibition of the Wnt/-catenin signaling pathway increases ciliary cell count, epithelial polarity, and barrier function, while inhibiting EMT, thereby reversing COPD characteristics

Younger adults were the primary driver of the rapid rise in using disposable vapes as the main type of vape between 2021 and 2023

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First described in neuronal cell death, oxidative stress induced by both neuronal excitotoxicity 29 and smoke exposure 13,16,17 leads to PARP-1 activation and initiation of the parthanatos pathway