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The main symptoms of tobacco addiction include strong cravings for nicotine, irritability, anxiety, and difficulty concentrating when not using tobacco

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However, most studies have compared e-cigarettes to placebo alone, or to nicotine replacement therapy, such as patches and lozenges, which help smokers manage their withdrawal symptoms

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Hookahs are among alternative tobacco products like chewing tobacco whose use has been on the rise in the U.S., especially among young people, the study authors note