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(eds) Principles of Biochemistry (Pearson Press, 2006)

Before we can talk numbers, we need to be on the same page about what we're measuring

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Preclinical research has employed various dosing approaches depending on the study type: In vitro cellular assays: 10100 nM (nanomolar concentrations) In vivo murine models: 520 g/kg (micrograms per kilogram body weight) Note: These represent different measurement systems appropriate to their respective study types

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