This is an area where the mechanism is well-characterized, the animal data is robust, and the safety profile appears favorable, but rigorous human trial data remains limited
Type of study: non-rct experimental Number of citations: 0 Year: 2024 Authors: Weiyi He, Chi Zhang, Huijung Lai, Guopeng Wu, Ming Xiong, Hui Peng, Ming Chen, Ke Wang Journal: Drug delivery and translational research Journal ranking: Q1 Key takeaways: Sph_12-38 combined with sponge spicules effectively treats acne, with a cure rate of 100% in vivo for rabbit ear acne after two weeks
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