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Efficacy of N-carbamoyl-L-glutamic acid for the treatment of inherited metabolic disorders

These include vitamin E, pioglitazone (PPAR agonist), obeticholic acid (farensoid X receptor agonist), cenicriviroc (CCR2/CCR5 antagonist), selonsertib (apoptosis signal-regulating kinase 1 inhibitor), and liraglutide (glucagon-like peptide 1 analogue) [136,137,138,139,140,141]

Resistant cells often exhibit increased invasiveness, motility, and tumorigenic potential, along with metabolic reprogramming

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