Accompanied by impaired BBB integrity, these peripheral immune factors gain access to the CNS, where they mediate neuroinflammatory responses, resulting in synaptic damage and neuronal dysfunction
The TYR gene, involved in melanin biosynthesis in melanocytes, has been significantly associated with vitiligo in the European population.63 The roles of many susceptibility loci remain unknown, highlighting the lack of understanding in the etiopathogenesis of vitiligo, which continues to be a challenge today
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Lets get anecdotes! He follows this up with, I think this could be big and, I did my research