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Research shows DSIP enhances enkephalin and endorphin signaling, the body's natural pain-relieving peptides, potentially providing analgesia without the addiction liability associated with exogenous opioid medications

Nature Rev Genet

It is suspected that, to counteract possible increases in UV-induced DNA damage, a greater requirement for the nuclear localization of this multienzyme complex and the availability of 5,10-methyleneTHF substrate is needed in the case of high UV exposure

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