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In oral supplementation trials (250-1000 mg/day for up to 6 months), side effects were mild and transient, including occasional gastrointestinal symptoms

This sequence of events is recapitulated in a humanized mouse model of diabetes, in which the presence of autoreactive T-cells alone was insufficient to induce disease, which was triggered only when -cells were stressed by the addition of the diabetogenic agent, streptozotocin (STZ) (32)

The researchers observed a significant increase in glutathione (GSH) synthesis (approximately 85 percent) and a 64 percent rise in total GSH levels in red blood cells

Vitamin E adds the benefits of antioxidants 1

PMID: 36737380