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The control group received saline instead of the peptide

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The study also revealed an unexpected pathway-dependent response: in telomerase-positive cancer cell lines, telomere elongation occurred through alternative lengthening of telomeres (ALT) activation rather than telomerase upregulation, suggesting that the AEDG sequences interaction with telomere maintenance pathways is more complex than initially characterized

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In some embodiments, the otic formulation or composition comprises about 30% by weight of the viscosity modulating agent(s)