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The swelled endoplasmic reticulum morphology was observed in the group of free OLE and PEG-T ECM -NS/OLE pretreated with pH 6.8 buffer, confirming ICD was elicited by OLE and PEG-T ECM -NS/OLE (Fig

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Their study showed the inactivation of LDH enzyme from plasma-induced modification of the secondary molecular structure as well as polymerization of the peptide chains after treatment for 300 s