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The exact pathophysiological mechanisms that heighten the risk of severe disease and mortality from COVID-19 in individuals with diabetes remain unclear [173,174,175]

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By reframing iron pathology as a problem of iron stasis rather than simple overload, we challenge conventional interpretations of iron in neurodegeneration and highlight the need to consider both iron immobilisation and metabolic insufficiency as central determinants of ferroptosis-related disease mechanisms

Fineschi, V., Viola, R

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