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60,61 Overview of ferroptosis Ferroptosis is a cellular response to oxidative stress that depends on excess iron, phospholipids (PLs) with polyunsaturated fatty acid chains (PUFAs), and ROS

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Phase Low range Daily dose 20-40 mcg/day Frequency Once daily Notes Most-cited beginner range

J Biol Chem 277:3288332891 Tanizawa Y, Nakai K, Sasaki T et al (2002) Unregulated elevation of glutamate dehydrogenase activity induces glutamine-stimulated insulin secretion: identification and characterization of a GLUD1 gene mutation and insulin secretion studies with MIN6 cells overexpressing the mutant glutamate dehydrogenase

Zhu, S., Barshow, S., Wildonger, J., Jan, L