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Across a pool of nine phase 2 and phase 3 clinical trials in people with T2D, acute pancreatitis was reported in 0.24% of participants with tirzepatide vs 0.13% with the comparators and acute gallbladder adverse events were reported in 1.1% of participants with tirzepatide vs 0.6% with the comparators [55]

PMID 7663973

Cell isolation and scRNA-seq experiments For all scRNA-seq experiments, Esm1-CreERT2 tg/+ and R26-mTmG tg/+ E18.0 embryos (injected with 2 mg 4-OHT at E17.0) were dissected in ice-cold PBS

Cell growth was monitored continuously for 100 h using the RTCA system

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