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In rat with the treatment of 10 g/Kg/day BPC 157, the concentration of BPC 157 was estimated to be less than 1 g/ml in the blood which was too low to cause hypotension or hemodynamic change as demonstrated by the lack of vasodilation in the present study 6

However, optimal success is associated with intravenous or subcutaneous injection , because these delivery methods have a high bioavailability

That changed in 2017, when researchers confirmed the presence of Epitalon in native pineal gland extracts, a discovery that validated its endogenous origin and helped explain its overlap with, but also differences from, Epithalamin [7]

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Preclinical studies frequently evaluate BPC-157 for its influence on healing across muscle, tendon, ligament, nerve, and intestinal tissues