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The extent of hepatic damage, along with levels of proinflammatory cytokines, chemokines, and neutrophil infiltration, remains comparable to that observed in wild-type controls

For women & men.

10.1186/S12933-018-0738-4 79 VauseT

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One investigation indicated that estrogen enhances C3 secretion in rat uterine epithelium, a phenomenon not replicated in the liver (82), suggesting that the effects of estrogen may be tissue-specific and cannot be generalized as universally activating the complement system