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This broad activity has made it an important subject of investigation in regenerative medicine, tissue engineering, sports science, and biotechnology research

Copper ions can catalyze the generation of reactive oxygen species, and copper homeostasis is maintained by a dedicated system of transporters, chaperones, and binding proteins (such as ceruloplasmin and albumin) that keep essentially no copper floating around unbound

A mouse was trained by being positioned on the widest section of the beam and then trained to step forward on the beam to return to its home cage

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Dose titration is essential for both options