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Unlike prior reviews, which often present descriptive overviews, this article emphasizes comparative evaluation of design principles, biological mechanisms, and translational hurdles, including biosafety, tumor heterogeneity, and large-scale manufacturability

Their study revealed that melanoma cells utilize PGC1 to enhance OXPHOS and ATP production, thereby promoting an invasive phenotype

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Studies have observed effects on: fibroblasts keratinocytes endothelial cells These cell types play essential roles in tissue remodeling and vascular regeneration, further explaining the peptide's role in wound healing

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